The 30 Best Hotels in Santa Cruz Region

Ranked 1 out of 77 in the Santa Cruz Region region, as well as being 1 of 21 for hotels in Samaipata.

• “We relaxed and enjoyed ourselves there. Highly recommended”
• “This place could do better, by installing airco, and add a coffee / station to the room”
• “Outstanding place! We stayed two nights and absolutely loved it.”
• See more reviews of El Pueblito Hotel Boutique

Ranked 2 out of 77 in the Santa Cruz Region region, as well as being 1 of 55 for hotels in Santa Cruz de la Sierra.

• “It was an interesting structure well worth visiting just for...”
• “A really great place. Beautiful room. Very nice and relaxed area.”
• “Almost perfect 👍”
• See more reviews of Alfonsina Hotel Boutique

Ranked 3 out of 77 in the Santa Cruz Region region, as well as being 4 of 21 for hotels in Samaipata.

• “Bugs and spiders all around the rooms, breakfast was not...”
• “Peaceful and comfortable stay”
• “Location is very convenient ”
• See more reviews of YVY CASA HOTEL

Ranked 4 out of 77 in the Santa Cruz Region region, as well as being 6 of 21 for hotels in Samaipata.

• “Nice clean room with safe parking”
• “A pleasant travel”
• “Perfect stay for Samapaita”
• See more reviews of La Vida es Bella

Ranked 5 out of 77 in the Santa Cruz Region region, as well as being 1 of 2 for hotels in San José de Chiquitos.

• “Nice new Pousada”
• “Great hotel and facilities - the pool and undercover patio...”
• “A peaceful retreat-like treasure tucked in between blossoming flowers and mature trees.”
• See more reviews of Rústico & Hotel Boutique Las Churapas

Ranked 6 out of 77 in the Santa Cruz Region region, as well as being 2 of 55 for hotels in Santa Cruz de la Sierra.

• “Nice staff and good breakfast”
• “Great stay”
• “Exceptionally helpful staff.”
• See more reviews of Cosmopolitano Hotel Boutique

Ranked 7 out of 77 in the Santa Cruz Region region, as well as being 3 of 55 for hotels in Santa Cruz de la Sierra.

• “Very good value, comfy room, good wifi, simple but nice...”
• “We liked everything and Marcela was a super host,.”
• “Hotel standard hi quality 3 star room.”
• See more reviews of Sur Backpackers

Ranked 8 out of 77 in the Santa Cruz Region region, as well as being 7 of 21 for hotels in Samaipata.

• “Hotel situated at short distance from centre. Views are beautiful”
• “Really peaceful.”
• “I liked everything !”
• See more reviews of Colina Verde

Ranked 9 out of 77 in the Santa Cruz Region region, as well as being 4 of 55 for hotels in Santa Cruz de la Sierra.

• “Awesome! Yo will not never regret!”
• “Great hotel and attention from staff”
• “Very clean and spacious room with a comfortable bed.”
• See more reviews of Chairu Eco Hotel

Ranked 10 out of 77 in the Santa Cruz Region region, as well as being 5 of 55 for hotels in Santa Cruz de la Sierra.

• “Pool área.”
• “Everything”
• “Attendance”
• See more reviews of Marriott Santa Cruz de la Sierra Hotel

Ranked 11 out of 77 in the Santa Cruz Region region, as well as being 6 of 55 for hotels in Santa Cruz de la Sierra.

• “perfect place to stay”
• “Wonderful option in Santa Cruz”
• “Luxurious feel while being very comfortable and homey”
• See more reviews of TRYP by Wyndham Santa Cruz

Ranked 12 out of 77 in the Santa Cruz Region region, as well as being 7 of 55 for hotels in Santa Cruz de la Sierra.

• “Central place to sleep well, enjoy breakfast and enjoy rainy days”
• “Loved the pools both outdoor and indoors.”
• “Very good pool and spa area.”
• See more reviews of Hotel Camino Real

Ranked 13 out of 77 in the Santa Cruz Region region, as well as being 8 of 21 for hotels in Samaipata.

• “Great host, excellent breakfast. A place you want to call home.”
• “The bed was comfy and it has an area to cook/store food...”
• “Terrific stay in the double tent”
• See more reviews of Los Aventureros

Ranked 14 out of 77 in the Santa Cruz Region region, as well as being 8 of 55 for hotels in Santa Cruz de la Sierra.

• “Pleasant”
• “Great pool and the hotel's garden where we also had...”
• “It was great, but the only issue was no hot showers”
• See more reviews of Hotel Cortez

Ranked 15 out of 77 in the Santa Cruz Region region, as well as being 9 of 55 for hotels in Santa Cruz de la Sierra.

• “The hostel Guajira is excellent.”
• “Pool, breakfast, friendly staff”
• “A tranquil stay in a busy city, nice, spacious room with air...”
• See more reviews of Guajira Hostel SCZ

Ranked 16 out of 77 in the Santa Cruz Region region, as well as being 10 of 55 for hotels in Santa Cruz de la Sierra.

• “Great option in Equipetrol”
• “Very nice and relaxing stay at the Hampton by Hilton Santan Cruz.”
• “The hotel didn't give me membership points. Very unprofessional, after contact, also unwilling to cooperate with the”
• See more reviews of Hampton by Hilton Santa Cruz

Ranked 17 out of 77 in the Santa Cruz Region region, as well as being 11 of 55 for hotels in Santa Cruz de la Sierra.

• “Breakfast is good.”
• “Wonderful experience”
• “Comfortable beds.”
• See more reviews of Novotel Santa Cruz De La Sierra

Ranked 18 out of 77 in the Santa Cruz Region region, as well as being 9 of 21 for hotels in Samaipata.

• “Lovely place”
• “Amazing, serene stay, unique experience and great amenities!”
• “Everything about La Vispera is amazing.”
• See more reviews of Finca La Vispera

Ranked 19 out of 77 in the Santa Cruz Region region, as well as being 12 of 55 for hotels in Santa Cruz de la Sierra.

• “Fun”
• “Ok”
• “Lovely hotel in the most interesting part of Santa Cruz.”
• See more reviews of Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ranked 20 out of 77 in the Santa Cruz Region region, as well as being 13 of 55 for hotels in Santa Cruz de la Sierra.

• “Great hotel, but don’t plan on working online”
• “Enjoy it”
• “Wonderful Business trip”
• See more reviews of Swissotel Santa Cruz de La Sierra

Ranked 21 out of 77 in the Santa Cruz Region region, as well as being 14 of 55 for hotels in Santa Cruz de la Sierra.

• “very happy, very good hotel”
• “Thank you for the comfortable stay”
• “Quiet, cozy, clean, with perfect breakfasts and very friendly staff!”
• See more reviews of Hotel By Armonía Santa Cruz

Ranked 22 out of 77 in the Santa Cruz Region region, as well as being 15 of 55 for hotels in Santa Cruz de la Sierra.

• “Nice!”
• “Everything was perfect and exceptional.”
• “Great staff, the building however leaves much to desire for its price.”
• See more reviews of Hotel Sirari By Regina

Ranked 23 out of 77 in the Santa Cruz Region region, as well as being 16 of 55 for hotels in Santa Cruz de la Sierra.

• “We are coming back”
• “No good, overpriced”
• “Highly recommended hotel in the affluent area of Santa Cruz.”
• See more reviews of Mai Suites Apart Hotel

Ranked 24 out of 77 in the Santa Cruz Region region, as well as being 17 of 55 for hotels in Santa Cruz de la Sierra.

• “Excellent value for money”
• “Big rooms with nice TV and big comfortable bed.”
• “Disappointed by the staff.”
• See more reviews of HOTEL OSHO

Ranked 25 out of 77 in the Santa Cruz Region region, as well as being 18 of 55 for hotels in Santa Cruz de la Sierra.

• “I enjoyed my stay at Delfines Collection. It is a modern hotel with all necessary amenities. Breakfast available.”
• “Really wonderful and comfortable hotel.”
• “Very pleasant, everybody were kind and servicial.”
• See more reviews of Delfines Collection Hotel by Mercure

Ranked 26 out of 77 in the Santa Cruz Region region, as well as being 19 of 55 for hotels in Santa Cruz de la Sierra.

• “Safe, friendly, welcoming and helpful!”
• “Nice hostel with swimming pool”
• “friendly hotel in safe and quiet neighbourhood within easy walking distance to centre”
• See more reviews of Lili's Hostel

Ranked 27 out of 77 in the Santa Cruz Region region, as well as being 1 of 1 for hotels in Montero.

• See more reviews of Residencial Pinocho

Ranked 28 out of 77 in the Santa Cruz Region region, as well as being 20 of 55 for hotels in Santa Cruz de la Sierra.

• “Excellent lobby, hallways, rooms”
• “Great”
• “Good location. Nice functional hotel”
• See more reviews of ibis Santa Cruz de la Sierra

Ranked 29 out of 77 in the Santa Cruz Region region, as well as being 1 of 1 for hotels in Camiri.

• “ottimo!”
• “It was perfect for the one night we stayed.”
• See more reviews of Hotel La Casona

Ranked 30 out of 77 in the Santa Cruz Region region, as well as being 21 of 55 for hotels in Santa Cruz de la Sierra.

• “Staff are very helpful. I met also Nicolas . He takes extra miles to help the guest .”
• “Very good location, the staff were super nice.”
• “The staff were all really lovely.”
• See more reviews of Nomad Hostel